Wednesday, April 24, 2013

Tennis-Myanmar cancels Davis Cup events over security concerns

April 23 (Reuters) - Myanmar has decided to opt out of hosting two Davis Cup events due to security concerns following last month's anti-Muslim riots, the head of the country's tennis association said on Tuesday.

Myanmar was to host the 2013 Asia/Oceania Zone Group III and IV events from April 22-May 5 in Yangon where 19 nations were set to take part.

Sectarian violence in Buddhist-majority Myanmar killed 43 people last month. Thousands, mostly Muslims, were driven from their homes and businesses as bloodshed spread across the Southeast Asian country.

"The government informed us on April 13 that we will need to postpone the events due to security reasons," Aung Maw Thein, president of the Tennis Federation of Myanmar, told Reuters.

"While the sports ministry did not divulge the details, I think it was because of last month's problems."

Players from a number of Muslim countries like Malaysia, Bahrain and Iraq were scheduled to play in the event and the International Tennis Federation has not yet decided on alternative dates and a venue.

The world governing body could not be reached for comment. (Reporting by Sudipto Ganguly in Mumbai; editing by Ed Osmond)

Source: http://news.yahoo.com/tennis-myanmar-cancels-davis-cup-events-over-security-122102926--ten.html

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Tuesday, April 16, 2013

Alleged 'iPad 5' case spotted in Hong Kong, hints at slimmer and narrower body

Alleged 'iPad 5' case spotted at Hong Kong Electronics Fair

Rumors of an upcoming iPad sporting a similar design as the iPad mini go as far back as late January this year, when our reliable friends at 9to5Mac shared some clear photos of a leaked chassis (check them out at the "More Coverage" link below). This was followed by an alleged photo of the front panel sent around earlier this month. But as before, cases for this unreleased "iPad 5" have also been making the rounds in China, and we've managed to get our hands on one at the Hong Kong Electronics Fair earlier today. It's the same old story according to a staff at the booth: the case is based on a leaked mold. Oops!

Compared to a similar case made for the two latest generations of the bigger iPad, this case again suggests a slimmer and narrower iPad is in the works, which would mean that this mysterious tablet is likely to have the same screen size but thinner left and right-side bezels -- just like the iPad mini. Similarly, the straighter edges support 9to5Mac's earlier leak of the iPad mini-like body. Let's just hope that Apple will still have a few surprises up its sleeves then, eh?

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Source: http://www.engadget.com/2013/04/16/ipad-5-case-leak/

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Monday, April 15, 2013

Nanosponges soak up toxins released by bacterial infections and venom

Apr. 14, 2013 ? Engineers at the University of California, San Diego have invented a "nanosponge" capable of safely removing a broad class of dangerous toxins from the bloodstream -- including toxins produced by MRSA, E. coli, poisonous snakes and bees. These nanosponges, which thus far have been studied in mice, can neutralize "pore-forming toxins," which destroy cells by poking holes in their cell membranes. Unlike other anti-toxin platforms that need to be custom synthesized for individual toxin type, the nanosponges can absorb different pore-forming toxins regardless of their molecular structures. In a study against alpha-haemolysin toxin from MRSA, pre-innoculation with nanosponges enabled 89 percent of mice to survive lethal doses.

Administering nanosponges after the lethal dose led to 44 percent survival.

The team, led by nanoengineers at the UC San Diego Jacobs School of Engineering, published the findings in Nature Nanotechnology April 14.

"This is a new way to remove toxins from the bloodstream," said Liangfang Zhang, a nanoengineering professor at the UC San Diego Jacobs School of Engineering and the senior author on the study. "Instead of creating specific treatments for individual toxins, we are developing a platform that can neutralize toxins caused by a wide range of pathogens, including MRSA and other antibiotic resistant bacteria," said Zhang. The work could also lead to non-species-specific therapies for venomous snake bites and bee stings, which would make it more likely that health care providers or at-risk individuals will have life-saving treatments available when they need them most.

The researchers are aiming to translate this work into approved therapies. "One of the first applications we are aiming for would be an anti-virulence treatment for MRSA. That's why we studied one of the most virulent toxins from MRSA in our experiments," said "Jack" Che-Ming Hu, the first author on the paper. Hu, now a post-doctoral researcher in Zhang's lab, earned his Ph.D. in bioengineering from UC San Diego in 2011.

Aspects of this work will be presented April 18 at Research Expo, the annual graduate student research and networking event of the UC San Diego Jacobs School of Engineering.

Nanosponges as Decoys

In order to evade the immune system and remain in circulation in the bloodstream, the nanosponges are wrapped in red blood cell membranes. This red blood cell cloaking technology was developed in Liangfang Zhang's lab at UC San Diego. The researchers previously demonstrated that nanoparticles disguised as red blood cells could be used to deliver cancer-fighting drugs directly to a tumor. Zhang also has a faculty appointment at the UC San Diego Moores Cancer Center.

Red blood cells are one of the primary targets of pore-forming toxins. When a group of toxins all puncture the same cell, forming a pore, uncontrolled ions rush in and the cell dies.

The nanosponges look like red blood cells, and therefore serve as red blood cell decoys that collect the toxins. The nanosponges absorb damaging toxins and divert them away from their cellular targets. The nanosponges had a half-life of 40 hours in the researchers' experiments in mice. Eventually the liver safely metabolized both the nanosponges and the sequestered toxins, with the liver incurring no discernible damage.

Each nanosponge has a diameter of approximately 85 nanometers and is made of a biocompatible polymer core wrapped in segments of red blood cells membranes.

Zhang's team separates the red blood cells from a small sample of blood using a centrifuge and then puts the cells into a solution that causes them to swell and burst, releasing hemoglobin and leaving RBC skins behind. The skins are then mixed with the ball-shaped nanoparticles until they are coated with a red blood cell membrane.

Just one red blood cell membrane can make thousands of nanosponges, which are 3,000 times smaller than a red blood cell. With a single dose, this army of nanosponges floods the blood stream, outnumbering red blood cells and intercepting toxins.

Based on test-tube experiments, the number of toxins each nanosponge could absorb depended on the toxin. For example, approximately 85 alpha-haemolysin toxin produced by MRSA, 30 stretpolysin-O toxins and 850 melittin monomoers, which are part of bee venom.

In mice, administering nanosponges and alpha-haemolysin toxin simultaneously at a toxin-to-nanosponge ratio of 70:1 neutralized the toxins and caused no discernible damage.

One next step, the researchers say, is to pursue clinical trials.

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The above story is reprinted from materials provided by University of California - San Diego, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Che-Ming J. Hu, Ronnie H. Fang, Jonathan Copp, Brian T. Luk, Liangfang Zhang. A biomimetic nanosponge that absorbs pore-forming toxins. Nature Nanotechnology, 2013; DOI: 10.1038/nnano.2013.54

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/JCulDU1774Y/130414193435.htm

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Commercial Law in the Legal Academy - Credit Slips

Brian Leiter's been running a poll about what areas of law and legal study deserve more attention from the legal academy. I was rather surprised by the choices in the poll: areas that I've always thought are well-covered like family law are included, while commercial law isn't even on the list. (One might express similar surprise about bankruptcy, which is a related, but distinct field, but that's another matter.) The poll includes "consumer law," but that's a pretty different area, as a lot of commercial law is about business-to-business transactions. ??

While many of us on this blog teach commercial law courses and write on areas touching commercial law (secured credit informs all our work), there really aren't very many people actively writing in the classical commercial law areas of sales, payments, and secured lending or even in commercial finance more broadly. Larry Garvin's written a whole article about this.

Maybe Brian's perspective is shaped by having taught at two schools (Texas and Chicago) that are unusually well stocked with people writing in commercial law and related areas. And perhaps commercial law is getting (very wrongly) lumped together with corporate law. (Does anyone even mention Delaware in commercial law classes? And does anyone mention the ALI or ULC in corporate law classes?) I have certainly observed a tendency among my colleagues writing in other areas to lump all business law classes together under the rubric of "corporate law". This is sort of like lumping admin and fed courts together.?

My sense is that the decline of academic commercial law is partially responsible for some of the astounding confusion regarding what is required to foreclose and the interplay between UCC Article 3, Article 9, real estate recordation, and MERS (an ersatz UCC Aritcle 8 attempt). Commercial law classes used to be standard law school courses. They're not any more at many schools, not least to the supply of academics working in the area, and that may be having real consequences for our legal system. ??

Source: http://www.creditslips.org/creditslips/2013/04/commercial-law-in-the-legal-academy.html

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Three people dead in suspected murder-suicide in Kansas

By Matthew Green HYDERABAD, Pakistan (Reuters) - When Veero Kolhi made the asset declaration required of candidates for Pakistan's May elections, she listed the following items: two beds, five mattresses, cooking pots and a bank account with life savings of 2,800 rupees ($28). While she may lack the fortune that is the customary entry ticket to Pakistani politics, Kolhi can make a claim that may resonate more powerfully with poor voters than the wearily familiar promises of her rivals. ...

Source: http://news.yahoo.com/three-people-found-shot-dead-house-topeka-kansas-161750886.html

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Sunday, April 14, 2013

Police: 3 found shot to death inside Kansas home

(AP) ? Police say three people have been found shot to death inside a home in Topeka, Kan.

Topeka police Lt. Scott Gilchrist says officers and emergency medical responders arrived after getting a 911 call around 9:15 p.m. CDT Friday from a woman at the home reporting that several people had been shot. He declined to give any identifying information about the three people who were found dead, including whether they lived in the house.

Gilchrist tells the Topeka Capital-Journal (http://bit.ly/10Sm6CZ ) that police were searching for a person of interest. He says the person isn't believed to be a threat to the general public.

The city of Topeka had recorded only two homicides this year prior to Friday, the newspaper reported.

___

Information from: The Topeka (Kan.) Capital-Journal, http://www.cjonline.com

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-04-13-Fatal%20Shootings-Kansas/id-f11c13727e90416182d0e8b4a22b7bde

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Music Gateway's mission to connect talent on a global scale | Music ...

The relationship between the music industry and the internet has been love/hate for a long time. But as artists and execs become increasingly savvy with the wealth of tech at their fingertips, the world wide web is now proving to be far more enabling than anything else.

While much has been achieved in distribution, marketing and communication online, artist, DJ, producer and record label owner Jon Skinner wants to empower the music industry at a much earlier stage in the process with his new music collaboration venture Music Gateway.

Inspired by a range of successful online solutions including social networks and file transfer mechanisms, Music Gateway is a business network for artists, producers and more. It?s a place where individuals can find each other, advertise jobs from session work to mastering and even pay fees remotely with a range of collaborative tools. We sat down with Skinner to find out more??

Tell us what Music Gateway is all about?

It's a business platform that allows people to find talent, find session work and collaborate worldwide. That?s the main purpose.

It's done on a project-by-project basis. If you're a producer, you can get work and do production or a remix or whatever it is that you offer. We are a one-stop solution for collaboration with three currencies ? Euros, US Dollars and Pounds - and people can make transactions via an internal account.

Rather than having to worry about going off and using third-party sites to pay people and there being issues, it offers protection via an online process. We can then act if there is an issue as a non-biased intermediary party.

The music industry is embracing new technology more than ever. Do you think working remotely could become commonplace in the future?

Absolutely. We?re not trying to put off people from working locally - there are some great benefits to being in the same room together - but, once people are connected, we share their information, so that they can then go away and start using tools. They can obviously use our tools, but there are other tools out there as well. These days, you can be in a different country and even jam using online tools.?

The world is such a small place now. We?re trying to encourage people to think a little bit bigger. If you're a session musician or a session singer, there's no reason why you can't be working with someone in France, in Europe, in Russia, or LA. It doesn't make a difference.

You don?t have to jump on a plane anymore. You can work very effectively remotely, and still have those close relationships with people, with these communication tools.

So yes, absolutely I think this is going to be commonplace, and technology is going to give us even better tools in years to come, which will make it even easier. Hopefully we will be part of that as we develop Music Gateway.

Is this just a connector for artists or could industry executives find it valuable as well...

We want publishers and artist management on board, as an example, because you could be on Music Gateway and represent a roster.

One of our project types is for mastering and studios, so we're connecting anyone that?s looking to get something mastered or needs a studio for a particular use. Rather than getting on Google and searching, you can actually use this. And because there?s a tender process, you can really review what studios match your needs. From the studio?s perspective, we're providing them with work.

We really want people to get in contact with us, we?re looking to get more partners on board. We?re really putting ourselves out there to try to make a difference to the industry.

But it's not just about supporting the industry, it?s about actually physically doing things together in a very proactive way. While you can share and promote your profile, you?re not just making random connections like you might do on a social network, which can be frustrating.

What?s the message to the rest of the industry at this point?

The site is live and we?ve partnered with a number of different industry people and organisations. What we're looking to do now is really work in conjunction with a lot of labels, because we feel that we have a platform that can help them from an A&R perspective to really develop their own artists and tap into other talent that?s out there. So, if you?re a Bristol label, you don't have to confine yourself to the southwest of England.

Hospital Records have come on board and are a prime example: they?ve got some artists in Europe, they?ve got some artists in the UK. They get inundated with demos, most of which are either not good enough or not relevant. With Music Gateway, we can save time and money targeted at getting people connected to the right talent. ?

Source: http://www.musicweek.com/news/read/music-gateway-s-mission-to-connect-talent-on-a-global-scale/054333

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